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Terpenes: The Other Powerful Compounds Found in Cannabis

THC and CBD are the most well-known of the chemical constituents found in cannabis, but these cannabinoids aren’t the only thing providing the source of the plant’s power. Terpenes are another grouping of beneficial natural compounds and provide much of the flavor and aroma associated with the cannabis plant and many other plants and food we enjoy.

Let’s take a closer look at the different terps and explore all the health benefits and effects they have to offer.

What are Terpenes?

Terpenes are a grouping of natural compounds found within almost every plant you can think of. These terpene (or terp) compounds are the source of the smell and taste you experience when consuming everything from citrus fruits to black pepper. They are also abundantly found in cannbis.

That lovely smell of pine trees you get when walking through the forest is caused by terpenes in the pine needles. The nostalgic aroma of lilacs in the spring? That’s from the terpenes found within the flower as well. Just about any strong scent you can imagine, in the plant world anyway, is created by terpenes.

Terpenes have received a lot of attention lately due to the rapid growth of the cannabis industry, which has led to a better understanding of all that these compounds can do. Over 20,000 terpenes are known to science, with most existing in plant life of one variety or another. Of these, nearly 200 can be found within the cannabis plant.

Every cannabis strain has a unique terpene profile that gives it specific characteristics in flavor, taste, and feel when consumed. Your favorite Sativa strain will have a different terpene profile than that heavy Indica you might smoke for its sedative effects.

Terpenes derived from other plant sources are often turned into essential oils that can be used for aromatherapy. They are also often used as additives in a variety of household products ranging from soaps to cleaning agents to perfumes.

Technically speaking, terpenoids are the compounds we enjoy after drying and curing cannabis flowers. Terpenoids differ from terpenes because oxidation has added extra atoms to their chemical construction. Terpenes are hydrocarbons that haven’t been denatured by oxidation, but in reality the terms terpene and terpenoid are used almost interchangeably.

Where do Terpenes come from?

Terpenes are found in the trichomes of the cannabis plant. Trichomes are the sticky resin glands found in cannabis flowers. This is the same part of the plant that produces the largest amount of cannabinoids, and the potency of a strain is often determined by levels of THC and CBD found in its trichomes.

Plants create terpenes for a variety of reasons, but the main biological reason is to keep predators away and/or attract pollinators. The strong smells that we associate with common plants can actually be a form of survival for those plants. We have selectively bred cannabis strains over the years, but terpenes were created naturally in the plant for these same defensive and pollination purposes.

Terpenes, Cannabis, and Cannabinoids

In this article, we will be looking at a few of the most common terpenes found in cannabis. Cannabis terpenes can provide a variety of beneficial health effects. They have been shown to have anti-inflammatory, antiseptic, antibacterial, antimicrobial, and antifungal properties, to name a few. Some common terpenes are even being studied for their anticancer properties.

When the many abundant terpenes found in the cannabis plant are combined with cannabinoids, something called the entourage effect occurs.

The entourage effect makes the beneficial properties of all these compounds work together to create effects that are more powerful than when they are isolated on their own. This synergy of terpenes and cannabinoids working together results in a ton of health benefits and other effects.

However, unlike cannabinoids, terpenes don’t interact directly with the endocannabinoid system. Cannabinoids like THC and CBD bind with the CB1 and CB2 receptors found within the human brain and nervous system. Terpenes bind to different receptors within the body.

Even though terpenes may not get all the same attention as their cannabinoid cousins THC and CBD, they are still important compounds found within the cannabis plant that give different strains their unique characteristics. The effects of THC in high concentrations can be psychoactive, which many recreational users enjoy, but CBD on its own is not psychoactive.

Terpenes are also not psychoactive, but they have medicinal properties that can be of great benefit for many cannabis users and can be harnessed from many other natural sources as well.

The Most Common Terpenes Found in Cannabis

As mentioned above, there are nearly 200 known terpenes found in the cannabis plant. More of these might be discovered as the cannabis industry continues to go mainstream and additional research and information becomes available.

Below you will find a breakdown of some of the most abundant terpenes found in cannabis, including limonene, myrcene, pinene, linalool, and caryophyllene. Different terpene profiles are found within various cannabis strains that can give them the flavor and aroma characteristics you may already be familiar with.

Now let’s take a look at the most common terpenes found in the cannabis plant.

Limonene – The Citrus Terpene

This is one of the most common terpenes found in various strains of cannabis. It’s typically associated with energizing effects that you find in Sativa varieties. If you notice a yellow color in the cannabis flowers, that’s a good sign it contains high concentrations of limonene.

  • Found in – lemons, limes, oranges, grapefruits, nearly all other citrus fruits, juniper, peppermint, rosemary.
  • Aroma – citrusy
  • Effects – energizing, enhanced mood, sense of well-being
  • Possible Medicinal Uses – antidepressant, antioxidant, anti-inflammatory, anti-cancer, pain relief (analgesic)
  • Strains with Limonene – Strawberry Banana, Do-Si-Dos, Purple Hindu Kush, Quantum Kush, Wedding Cake, White Fire OG

Myrcene – The Most Common Cannabis Terpene

Myrcene is the most abundant terpene found in cannabis and is present in nearly all strains at some level. It has calming effects and is found in many Indica varieties. Myrcene is said to make up a significant percentage of the terpene profile of some of the most popular cannabis strains.

  • Found in – mango, lemongrass, cloves, thyme, geraniums, hops, balsamic vinegar
  • Aroma – earthy with hints of clove and citrus
  • Effects – calming, relaxing
  • Possible Medicinal Uses – anti-anxiety, helps promote restful sleep, anti-inflammatory, analgesic, antimicrobial, antiseptic, antioxidant, muscle relaxant
  • Strains with Myrcene – OG Kush, Granddaddy Purple, Blue Dream, Cherry Pie, Remedy, Grape Ape, 9 Pound Hammer, Tangie, Harlequin

Pinene – Nature’s Most Abundant Terpene

Pinene is the most common terpene in the world and is also an abundant terpene in cannabis. It can promote both a calming and relaxing effect and is the scent you smell while going through a walk in the forest and get a whiff of pine needles and conifer trees. Some people say pinene is one reason a walk through the woods can make you feel so good.

  • Found in – pine needles, conifer, cedar, parsley basil, rosemary
  • Aroma – pine
  • Effects – focused but energized and can help with memory, might counteract some of the psychoactive effects of THC
  • Possible Medicinal Uses – anti-anxiety, anti-cancer, bronchodilator used in treatment of asthma, analgesic, anti-inflammatory, antibacterial
  • Strains with Pinene – Big Smooth, Strawberry Cough, Critical Mass, Snoop’s Dream, Blue Dream, Grape Ape, Cotton Candy Kush, Harlequin

Caryophyllene (Beta-caryophyllene) – The Endocannabinoid Terpene

Caryophyllene is unique in that, like a cannabinoid, it can also interact directly with the endocannabinoid system at CB2 receptors. It is the only terpene known to have this property.

  • Found in – black pepper, cinnamon, basil, all-spice, fig, cloves, oregano
  • Aroma – spicy, peppery, earthy, herbal
  • Effects – stress relief, calming and relaxing
  • Possible Medicinal Uses – analgesic, antioxidant, anti-inflammatory properties, antianxiety, may help with depression, can help with insomnia
  • Strains with Caryophyllene – Super Silver Haze, Rock Star, Girl Scout Cookies, Skywalker, Original Glue, Purple Punch, GSC, Death Star, Chemdog, Bubba Kush

Terpinolene – The Energy Terp

Terpinolene is found in many cannabis strains but typically only in smaller amounts. That means it is less common than the others on this list but still has some great benefits to offer. It has a smell that is hard to pinpoint and can provide uplifting and energizing effects.

  • Found in – cumin, pine, lime blossoms, lilacs, nutmeg
  • Aroma – a mix of many aromas including citrusy, piney, and floral.
  • Effects – uplifting and energizing
  • Possible Medicinal Uses – antibacterial, antifungal, anticancer, can possibly help with heart disease.
  • Strains with Terpinolene – Durban Poison, XJ-13, Ghost Train Haze, Orange Cookies, Golden Goat, Golden Pineapple, Dutch Treat, Jack Herer

Humulene – The Earthy Terpene

Humulene is a terpene found in cannabis strains that has also been used in traditional medicine for many years. It has more of a slight and earthy smell compared to other terpenes that are more in your face. It has a variety of benefits and is a sesquiterpene similar to caryophyllene.

  • Found in – coriander, clove, basil, black pepper, ginger, sage, ginseng, hops
  • Aroma – earthy and herbal
  • Effects – plays an important role in the life cycle of the cannabis plant, a variety of beneficial uses—some of which are subtle
  • Possible Medicinal Uses – antibacterial, anticancer, analgesic, anti-inflammatory
  • Strains with Humulene – Liberty Haze, Gelato, Sour Diesel, Sherbet, Girl Scout Cookies, Death Star, Original Glue, Candyland

Linalool – The Relaxation Terpene

Linalool is another terpene with the ability to help with relaxation and promote feelings of calmness. These same properties that help you relax can also help improve your mood, so it can provide feelings of happiness as well.

  • Found in – lavender, mint, citrus, cinnamon, birch bark
  • Aroma – floral
  • Effects – calming and relaxing, can help improve mood.
  • Possible Medicinal Uses – antianxiety, antidepressant, antimicrobial, antibacterial, stress relief, anti-cancer, analgesic, sleep aid
  • Strains with Linalool – Special Kush, Zkittlez, Amnesia Haze, OG Shark, Kosher Kush, Do-Si-Dos, Scooby Snacks

Ocimene – The Floral Terpene

Ocimene is found within many strains of cannabis but more so in other plants in the natural world. It has uplifting and energizing effects and the potential for some solid medicinal benefits that are still being studied.

  • Found in – orchids, hops, basil, kumquats, mango, bergamot, parsley, mint
  • Aroma – floral and sweet without being too much
  • Effects – uplifting in a subtle way
  • Possible Medicinal Uses – antiviral, anti-inflammatory properties, antifungal, antiseptic, decongestant, anti-inflammatory, antioxidant
  • Strains with Ocimene – Green Crack, Golden Goat, Space Queen, Dutch Treat, Amnesia, Clementine, Golden Pineapple, J1

The Less-Common Terpenes

There are several other terpenes not listed here such as geraniol, isoprene, and camphene. While these can be present in some strains of Cannabis sativa, they aren’t found in abundance, so they don’t make the list for the most common terpenes.

You can enjoy the benefits of any of the terpenes described here by smoking your favorite strain or by using other products such as cannabis extracts in the form of edibles or liquid extract for vaping.

How do Terpenes affect the body?

Terpenes can affect the body in multiple ways. Whether you inhale natural terpenes in the form of a plant’s scent or ingest them when you enjoy a cannabis edible, they can have a quick and pronounced interaction within some systems in the body.

In terms of the effects cannabis-based terpenes can have in your body, they are very much related to cannabinoids in how they bind with receptors in the brain and the endocannabinoid system in particular. Cannabinoids like CBD and THC work in conjunction with the terpenes found in your favorite cannabis strain and have a complementary effect on one another.

From a pharmacological perspective, meaning how these compounds directly interact with bodily systems, terpenes can help to release certain neurotransmitters in the brain that can help increase the beneficial or sought after effects of cannabis.

Mood-boosting chemicals such as dopamine, serotonin, and norepinephrine can be encouraged when both cannabinoids and terpenes enter the bloodstream and reach receptors in the brain that then stimulate their production.

Terpenes can have this effect within the body on their own, but they seem to be much more powerful when combined with the many cannabinoids found in cannabis. They kind of act like a power boost for certain benefits that many cannabis users enjoy.

Your favorite strain that helps calm you down or give you energy may just be attributed to the specific terpenes found within it. When you smoke or ingest it, the terpenes and cannabinoids work together to help promote the release of chemicals in the brain that lead to that effect.

Terpenes also seem to have an effect within the body on a psychological level as well. That’s why the smell of lavender can help calm you down if you are feeling anxious, or another scent can make you feel somewhat energetic. While this isn’t a direct chemical reaction in the body, it is a real effect that you experience. Simply smelling a bud of cannabis can trigger some of the same responses you might experience when smoking or ingesting it. These effects are usually less pronounced, but it’s pretty intriguing that they occur in the first place.

With more research being done into terpenes and cannabinoids and the effects they have within the body, a better understanding of how they work synergistically is sure to be revealed. Science is only beginning to unlock the true potential of these remarkable compounds.

Are Terpenes Safe?

A common question that many people have when consuming any type of compound or chemical, whether they are created by science or found in nature, is if they are safe for human consumption. This is a very valid concern as the body can react in unexpected ways to any foreign substance, with sometimes negative results.

Since most terpenes are found in nature, they are typically safe to consume. While the body might react in different ways to different terpenes, they are rarely dangerous in any way. Some people might have an allergy to a specific plant or smell, and this can partly be attributed to the terpenes found within them and how they interact with an individual’s unique body chemistry.

The specific terpenes found within the cannabis plant and its many strains are generally safe to consume without worry. In fact, the Food and Drug Administration has put them on their GRAS list, which stands for Generally Recognized as Safe. This is good peace of mind for anyone who has any safety concerns about terpenes, and the FDA is the primary regulatory agency for food products and supplements. The FDA is pretty strict about what products they put on this list, so that’s another sign that terpenes are safe.

It is important to note that everyone can react differently to terpenes and cannabinoids, however. One person’s reaction does not necessarily mean that you will have the same exact experience. This doesn’t indicate that it is going to be unsafe, but it may result in some effects that are unwanted. Dosing is another consideration to take into account here. If you smoke or vape a heavy dose of cannabis, you will get a higher dose of both cannabinoids and terpenes.

While most cannabis users have experienced the effects of this at one point or another, it can be a lot to handle for the first time user. But even though this can lead to anxiety and a feeling of panic, it will pass fairly quickly and not pose any long-term or serious safety concerns to your health.

Are there terpenes in CBD?

If you are reading this guide, you may be learning about terpenes for the first time. And another good question that people in this camp often wonder about is if terpenes are found in CBD. The answer depends on what type of CBD product you choose to consume. Terpenes are not found in all types of CBD products, but this comes down to how the product is created, its extraction process, and the type of initial plant product it is derived from.

In the world of CBD oil, there are a couple of different options available for you to choose from. You have probably heard of the common cannabis terms isolate and full-spectrum. CBD isolate indicates that CBD is the only compound present within the oil. Producers use a process to isolate this form of CBD from any other type of compound or chemical – meaning it will not have any terpenes present in it. Full-spectrum CBD oil is different in that it doesn’t attempt to isolate the compound and therefore can have other things present within it. Full-spectrum CBD will have terpenes in it, and potentially various cannabinoids as well.

Sometimes CBD producers will take a CBD isolate and then add terpenes back into the product as well. This can have an impact on both the flavor and effect of the product. Some companies are actually trying to create specific products for specific purposes and harnessing the power of terpenes to do this. By first isolating CBD and then adding certain terpenes back into the mix, they are able to create a product that can have specific benefits that a user might be seeking. Full-spectrum products that already have terpenes in them, can have increased benefits over isolate. However, their effects might not be as specifically targeted as the recipe-like terpene products that can now be found.

If you know that you only want CBD and are trying to avoid any added substances, terpenes, or otherwise, CBD isolate is a good option to use. If you like the advantage of having extra cannabinoids and terpenes within a product because of the synergistic effect this can have, get a full spectrum product or a CBD isolate that has had terpenes added to it. All varieties of the cannabis or hemp plant that are high in CBD will also have terpenes in it. An isolated CBD plant is something that doesn’t exist in nature.

Do terpenes get you high?

While terpenes can cause any number of benefits on their own or when consumed alongside cannabinoids, they aren’t psychoactive compounds. That means they will not get you high. The high that you experience when consuming cannabis is almost entirely caused by THC, the psychoactive cannabinoid that many people are well aware of. While there are other cannabinoids within cannabinoid varieties that can also have a somewhat psychoactive effect, terpenes are not one of these.

And even though terpenes can cause you to have both a physiological and psychological reaction, that is far different than a psychoactive one. You aren’t going to have to worry about driving a car or getting paranoid if you simply take a whiff of a flower, cannabis or otherwise, that is packed full of terpenes. These compounds do not react with the receptors in your brain quite the same way as cannabinoids, and THC is the main ingredient for getting high and cannabis anyway.

If you really sniff or inhale anything aromatic, which means it is heavy in terpenes, you might get dizzy or have another sensation. But this is more likely caused by becoming short of breath and a lack of oxygen to the brain than anything that is actually occurring with the terpenes interacting inside of your body and brain. Terpenes do have plenty of effects and benefits that occur when you ingest or smell them, but they won’t inebriate you or alter your reality in any sort of significant way.

Final Thoughts

Terpenes are an important part of cannabis, and of the entire experience of consuming cannabis products. Since terpenes are safe to consume, it’s more important to consider the effects that certain terpenes can have to limit any undesirable effects. You can look at the sections above to get a general idea of what to expect out of some common strains and the terpenes that are found within them.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

 

Cannabis Patents

Marijuana has been a Schedule I drug in the United States since the Controlled Substances Act of 1970. Richard Nixon and his ‘war on drugs’ didn’t care about loads of evidence showing all the medicinal uses of cannabis patents; he simply wanted marijuana banned. In fact, it was the National Commission on Marihuana and Drug Abuse that Nixon himself hired to prove the dangers of cannabis who ended up recommending cannabis patents instead be decriminalized based on the results of their findings. Unfortunately, the reasons for the banning of marijuana were not necessarily fair or logical, but here we are in 2019, and it is still a highly controlled substance.

Throughout the years, as marijuana has been up for rescheduling again and again, the Drug Enforcement Administration (DEA) continues to refuse regardless of studies showing marijuana’s numerous benefits. The DEA’s most recent refusal to reschedule marijuana happened in 2016. For the record, a Schedule I drug is one that has ‘no current accepted medicinal value in the United States.’ That’s where we’re at with marijuana currently, which seems ludicrous, especially considering that opioids have created an unprecedented crisis in the country for all the harm they cause. Still opioids are more useful than marijuana in the eyes of the government.

All this isn’t really news. We know the national government has long been ignoring the benefits of marijuana that countless studies have shown. What is curious, however, is that, despite keeping marijuana a Schedule I drug, the US Department of Health and Human Services (HHS) has a patent on certain parts of the marijuana plant. Patent no. 6,630,507 covers:

  • the potential use of non-psychoactive cannabinoids to protect the brain from damage or degeneration caused by certain diseases, such as cirrhosis.

The patent also covers cannabinoids that are useful in treating things like Alzheimer’s, Parkinson’s, and HIV dementia.

How can it be that the government keeps cannabis a Schedule I drug while at the same time having a patent on the plant for its medicinal uses? Is this utter hypocrisy, or are we missing something?

To be clear, the HHS does not have a cannabis patents on marijuana as a whole. The patent covers only parts of the plant, including the natural and synthetic non-psychoactive cannabinoids, including cannabidiol (CBD). CBD, as most cannabis-friendly folks know at this point, does not get anyone high. It is for this reason it seems there is some kind of loophole that has permitted cannabis patent no. 6,630,507 to go through.

How The US Government First Got a Cannabis Patents

Back in 1999, three scientists from the National Institute of Mental Health (NIMH), Hampson, Axelrod, and Grimaldi, filed for patent no. 6,630,507. In 2003, the HHS gave them their cannabis patents. NIMH is part of the larger government agency, the National Institute on Drug Abuse (NIDA). NIDA is notorious for their anti-marijuana stance, publishing lots of studies that show marijuana is very bad.

Perhaps the fact that there are more than 20,000 studies that have shown marijuana’s positive medical effects is what led to NIDA granting this marijuana patent, especially since it only covers CBD, the non-psychoactive elements of the plant, for treating neurological conditions. Within the patent, it states the scientists discovered that there are antioxidant properties in CBD. It also states that any cannabinoid that acts through receptors such as THC is not covered. Still, issuing the patent in the first place seems to contradict marijuana being a Schedule I drug, seeing that the schedule itself is meant for substances that are dangerous and not useful for medical purposes in any way.

As time passes, cannabis research provides more and more peer-reviewed evidence that marijuana is effective in treating a vast array of medical issues, including cancer, glaucoma, multiple sclerosis, chronic pain, arthritis, asthma, insomnia, depression, and epilepsy. What’s more, it is also less expensive and less dangerous than many drugs currently used to treat many of these conditions. It makes sense that a patent for marijuana would be issued to create a better quality of life for people afflicted with any of these conditions. What does not make sense is why it is still a Schedule I drug.

Why Is Cannabis Still So Illegal Despite This Patent?

The National Institute of Health (NIH) hires about 6,000 Ph.D. scientists to oversee all the studies in its institutions. If a notable discovery is made, the decision must be made about whether to file a patent. Patent no. 6,630,507 was granted as a result of research showing the possibility that parts of the cannabis plant, those that are non-psychoactive, are effective in the treatment of neurological diseases. Because relief from these diseases via the cannabis plant is possible without getting high from THC, the patent was granted.

The patent does not say there is proof that treatment using cannabinoids is effective. That would require laboratory purification and synthesis of the compound, not to mention loads of animal and human testing, plus being approved by the FDA once all that is done, like what has happened with Epidiolex.

In other words, the patent was granted because–at the time it was applied-for–there was a possibility that it could be effective, and worthy of further research. In the meantime, the government has kept its potential largely hidden from the public and classified as a Schedule I drug.

Green in More Places Than One

That patent has a bit more complexity than just looking into the medical possibilities of certain parts of the cannabis plant, however. The government may have more than just public health in mind when this patent went through. There’s a lot of money to be made in the event that elements of the cannabis plant do provide effective medical treatments. In fact, the amount of money that certain firms could come into as a result of patent no. 6,630,507 is no small sum. This begs the question: who exactly is set to be making money off this deal?

Kannalife Sciences Inc. is a company based in New York. They obtained a license from the NIH in 2011 to use some of the patent’s technology. What they want to do is develop CBD-based medicines to treat hepatic encephalopathy (CTE), a form of brain damage. As such, Kannalife can now use the patented technology for research. In the event that they develop a successful drug, Kannalife CEO Dean Petkanas mentioned the government would get a huge percentage of sales that could result in six-figure royalties.

If the government has known about these potential benefits of parts of the cannabis plant, why did they deny the rescheduling of marijuana in 2016? Keeping marijuana a Schedule I drug makes it harder for other research to be done, which benefits Kannalife and the US government financially.

Before 2016, Kannalife was the only company with a license to a piece of the patent. That changed when GW Pharmaceuticals also got its own piece of the patent as it completed its new drug application for Epidolex. Epidolex is a drug developed using CBD to treat seizures. Upon approval, the drug could earn upwards of $2.2 billion a year. Seeing that the government will receive royalties from that as well, it raises questions about the real reasons marijuana has been kept a Schedule I drug.

With the legalization across many US states in recent years, companies have been both applying for and getting approved for patents using cannabinoids like CBD to make medicine for a variety of medical conditions. In 2018, the US Patent and Trademark Office issued 39 patents which contained the words marijuana or cannabis in their summaries. In 2017, that number was 29, and in 2016, only 14. Those patents are for different uses of cannabinoids than patent no. 6,630,507, though still completely leaving out THC.

Patent no. 6,630,507 expires on April 21, 2019. After that, using the cannabinoids outlined in the patent will be fair game for everyone, though any drugs created will still have to be approved by the FDA.

A Case of Hypocrisy Cannabis Patents

Even professionals like Gregory F. Wesner, a patent and trademark attorney, don’t deny the hypocrisy in patent no. 6,630,507. By classifying marijuana as a Schedule I drug, it means that all parts of the plant are deemed unsafe for consumption, according to the DEA and US government. Yet, the US government has a patent on synthetic cannabinoid drugs derived from marijuana, which are then being approved by the FDA.

Legalizing marijuana nationally would dramatically change the distribution of profits from marijuana, as many people and companies would be filing for patents almost immediately. The low number of patents approved per year despite abundant research showing the medical benefits of the plant serves to show how stifled the industry is by keeping marijuana a Schedule I drug. This begs the question: why does the US government continues to keep marijuana a Schedule I drug? Companies like Kannalife and GW Pharmaceuticals would be up against competition instead of having the industry nearly all to themselves, which would would cut into both their own profit and the profit the government. Companies like Kannalife and GW Pharmaceuticals would be up against competition instead of having the industry nearly all to themselves, which would would cut into both their own profit and the profit the government.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products (such as the Delta 8 gummies and Delta 9 gummies) are of the highest quality and safety standards.

How Much THC is in Weed?

THC potency in cannabis can range from near 0% in hemp-derived CBD products to over 90+ percent THC strains of marijuana concentrates. And THC potency is dynamic, with various factors affecting THC levels, from seed to smoke.

It’s often more than reading numbers on a label to figure out THC concentrations. In this guide, we’ll cover:

  • How much THC is in cannabis
  • Types of THC present in recreational cannabis and medical marijuana
  • How to calculate THC content
  • How much THC content determines how high potency cannabis strains are

Read on to learn about THC content in cannabis.

How Much THC is in Weed?

The amount of THC in cannabis varies significantly between different products, strains, and even batches or plants. It even varies over time.

When researchers first accurately measured THC potency in the 1960s, THC content in many strains registered at about 4 to 5%. However, THC content in most strains growers are cultivating is significantly higher today. As more states trend toward legalizing recreational cannabis, more breeders are experimenting with new cannabis strains and working to produce high THC flower.

Often, the strains that are naturally high in THC lean to the sativa dominant side and produce more mental effects. In contrast, indica dominant strains tend to feature both THC and CBD, which offsets those specific THC effects.

According to the Drug Enforcement Administration (DEA), in 2018, the average THC potency of the marijuana seized was around 15%. Today, it’s common to find cannabis flower in legal dispensaries with well over 20% THC, and some higher THC strains with over 30%.

Type of produce further influences the range of THC content. Consumers can choose from classic cannabis flower, as well as marijuana edibles, topicals, tinctures, and concentrates of all different strengths.

Manufacturers extract cannabinoids and terpenes from cannabis flower to make concentrates. After discarding excess organic matter, these concentrated marijuana products contain at least 70% THC, and some deliver over 90% THC.

How is THC Content Calculated?

The THC content is measured in a percentage that indicates its potency. Most legal cannabis states require products to be tested for THC content as well as minor cannabinoids, and to display this information on the label.

The cannabis industry is largely unregulated, so there is substantial variation between cannabis products. Usually, however, the label will list THC, THCA (tetrahydrocannabinolic acid), CBD, CBDA, and sometimes minor cannabinoids such as CBN cannabigerol (CBG) its acidic precursor, CBGA.

The presence of other cannabinoids and terpenes are other key factors in how potent cannabis products are. This synergistic way that these compounds work together is called the entourage effect.

What do these THC percentages mean? You’ll notice that there’s much more THCA than THC in cannabis. Cannabis flower often contains over 20% THCA but just 1 or 2% THC.

THCA, a non-intoxicating precursor cannabinoid, produces THC through decarboxylation, a heating process. In other words, it takes the smoking or vaping process to activate that cannabinoid. This process also occurs naturally over time.

This is why eating plain, unburned cannabis flower is not really capable of causing serious impairment. This is also why subjecting flower to decarboxylation makes it more potent. It is this THC content, the total THC content after decarboxylation that mostly determines THC potency.

Why is total THC value less than THCA value on cannabis products? In part because THC is lighter than THCA. Additionally, the decarboxylation process is not entirely efficient, so some THCA molecules fail to convert to THC and instead degrade into CBN, either during improper storage, dabbing at high temperature, or a similar situation.

THC Content: A Simple Equation for the Most Accurate Number

There is a basic estimate in equation form you can use to calculate THC content. It considers constants such as the weight difference between THC and THCA and the inefficient THC conversion process as well as unique factors such as the amount of THC already present in the cannabis product.

The assumption is that about 75% converts and THC is about 87% of the weight of THCA. This means that the equation looks like this:

(0.75 x 0.877 x %THCA) + %THC = total THC content

For example, a cannabis product with 28% THCA and 2% THC, this is what you would end up with:

(0.75 x 0.877 x %20THCA) + %1 THC = 20.184% total THC content

What Type of THC is in Cannabis?

There is more than one kind of THC; there are multiple chemical analogs, each with its own unique structure that allows it to impart unique effects.

Delta-9 THC. This is the OG of THCs. The psychoactive effects we all know and love from cannabis come from delta-9 THC and the unique double bond structure on the 9th carbon atom of its molecular chain. This allows it to bind with CB1 receptors in the body’s endocannabinoid system (ECS), which are mostly responsible for psychoactive effects. Delta 9’s 5-term side alkyl carbon atom chain also enhances the effects of THC on the body.

Tetrahydrocannabivarin (THCV). After THCA decarboxylation there are actually two compounds produced in relative abundance: THC is the main product and the second most abundant result is tetrahydrocannabivarin or THCV. THCV doesn’t bind as strongly to the body’s CB1 receptors, having a 3-term chain not a 5-term chain as a byproduct of THCA decarboxylation, so at low doses THCV’s psychoactive effects are less pronounced than those of delta 9.

Tetrahydrocannabiorcol (THCC). THCC is a non-psychoactive compound present in cannabis pollen and an analog of THC. In terms of effects, it’s most similar to CBD. THCC is unique for its capacity to bind to the vanilloid receptors (TRPA1), although it doesn’t bind well to either the CB1 or CB2 receptors.

Tetrahydrocannabiphorol (THCP). Discovered in 2019, THCP has two more carbon atoms than delta 9 THC on its alkyl side chain. This longer side chain means stronger psychoactive effects—as many as 33 times more potent.

Delta-7 (THC). Despite having first been synthesized in the 1940s, research into delta 7 THC has been extremely limited. However, we know that delta 7’s double bond is on the seventh carbon atom, and due to this and what we know about other cannabinoids such as delta-8 THC we surmise that delta-7 is significantly less potent than delta 9.

Delta-8 (THC). Another THC analog, delta 8 THC has its double bond on the eighth carbon atom. Delta 8 cannabis consumers report a much milder, more pleasant high from this product which has achieved a loyal following.

Delta-10 (THC). Like delta-8 THC, delta-10 THC is present in trace amounts naturally in cannabis. However, the double bond for delta-10 is located on the tenth carbon atom. As you might guess, delta-10 is even milder in terms of psychoactive effects than delta-8.

Which Factors Affect THC Content?

Many factors affect the THC content of cannabis, such as:

Genetics. The genetics of the cannabis plant is a critical factor influencing THC content.

Each unique genotype even within a strain acts as a blueprint for phenotype and consumer experience, as well as how the live plant responds to conditions in the environment.

Other enzymes and cannabinoids. THC content in a specific strain is heavily determined by the ratio of THC to CBD. This ratio influences classic cannabis side effects; higher levels of THC cause more side effects, whereas higher CBD levels counteract these kinds of side effects. This is why some cannabis strains are highlighted as CBD-dominant or balanced. Depending on which enzymes are in a strain, CBGA will convert into either CBDA or THCA, for example. The latter kind will produce and contain much more THC—so dispensaries are interested in finding growers who can produce those strains.

Environmental factors. Environmental factors also affect THC content, including nutrient availability, quality of soil (if used), the growing method used, the light source and spectrum, temperature, pH and CO2 levels, and humidity. Suboptimal conditions force the cannabis plant to prioritize survival over cannabinoid production.

What’s the Average Dose of THC?

The average dose of THC differs from person to person since everyone has their own tolerance levels. These are based on many factors, including prior cannabis use, age, sex, weight, the individual’s endocannabinoid system, and existing physical and mental health.

In general, though, less than 10 mg of THC is considered a low dose, while a dose between 10 and 30 mg of THC would be strong for beginners and have considerable effects even on experienced users.

Doses above 30 mg of THC are very potent and should only really be consumed by regular cannabis users. One area that causes trouble for new users in particular? Cannabis edibles and high-THC cannabis tinctures invariably result in a stronger high. First-time users beware.

And how much THC is in a joint? This depends not only on what we’re already covered, but also on the amount of THC lost to good old-fashioned combustion.

A one gram, 1000 mg joint of cannabis flower and 25% THC content contains 250 mg of THC. That’s a lot for one at once. However, you probably lose at least half burning away.

Final Thoughts: How Much THC Is In Cannabis?

There are so many factors that impact THC content, and in the end, you’re really just estimating unless you have precise instruments. Everything from the weather to terpenes and other cannabinoids play a role in the amount of THC in a cannabis product.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

THCV Effects

What is THCV effects? Tetrahydrocannabivarin (abbreviated Δ9-THCV or just THCV) is a psychoactive cannabinoid most often found in Sativa-dominant strains of the Cannabis sativa plant such as Durban Poison or Jack Herer.

THCV is known to produce alertness, appetite suppression, and a more motivated, energized feeling of euphoria. For this reason, THCV products are often recommended for daytime use or medical cannabis patients who want less of the traditional cannabis side effects.

Ready to learn everything you need to know about THCV effects? In this post we’ll cover:

  • All of the basics about the phytocannabinoid tetrahydrocannabivarian (THCV)
  • Its role in the cannabis plant, and how it interacts with cannabinoid receptors in your body’s endocannabinoid system (ECS)
  • The unique health benefits and different effects of THCV
  • Where to buy THCV and other cannabis products

And much more. Read on to learn more about this interesting and little-known plant cannabinoid!

The Science of THCV Effects: The Basics

Delta-9 tetrahydrocannabivarin (THCV) is a compound derived from the cannabis plant. As you might guess based on its name, its pharmacology is very similar to that of delta-9 tetrahydrocannabinol (THC) as well as analogs such as delta-8 THC.

How long it takes for effects of THCV to hit you and how intense they are depends in part on how large your dose is and what form it takes. For example, edibles take longer to feel the effects from, but they also last longer and feel more intense.

The main difference between THC and THCV is a lack of psychoactive effects.

In fact, at least one study found that low doses of THCV taken intravenously cause the compound to act as an agonist in the nervous system, reducing the classic effects of regular THC such as paranoia and dry eyes. This is principally because unlike THC, THCV has a lower affinity for the CB1 receptor, which produces more mental effects. Instead, THCV is more interactive with the CB2 receptor, which is responsible for more pain and appetite control.

Health Benefits of THCV Effects

THCV’s unique properties and health benefits make it different from the more common cannabinoids, such as THC and cannabidiol (CBD) and minor cannabinoids as well, such as cannabigerol (CBG) or cannabinol (CBN).

Another important property centers on appetite control—earning it the nickname “diet weed.” But does it really work for appetite suppression or weight loss? For people struggling with obesity or diabetes the answer may be yes.

In rodent studies, THCV increases satiety, decreases appetite, and up-regulates energy metabolism. THCV is also more useful for blood sugar/glucose metabolism, glycemic control, and energy regulation than is THC. Research has also demonstrated that THCV reduced fasting plasma glucose concentrations among people with type 2 diabetes compared to a placebo-controlled group.

[Learn more about THCV, diabetes, and obesity at DOI 10.1186/s42238-020-0016-7]

Research indicates that THCV may contribute to bone growth, and may therefore have therapeutic effects in treating bone-degenerative diseases such as osteoporosis.

According to research in animal models, THCV may have a neuroprotective effect, potentially relieving the symptoms of Parkinson’s disease and Alzheimer’s disease. It may also play a role in the treatment of epilepsy.

Of course, THC is better for people struggling with cachexia and related issues. If this is your health struggle, the munchies are definitely your friend, and you might want to avoid high doses of THCV.

Where to Buy THCV Products

This is one of those products that is almost always best bought online. This is because as a specialty item, it can be hard to find.

THCV occurs in very small amounts in the cannabis plant in nature, so most of the THCV products you find for sale are made by isolating the compound in a lab. This labor-intensive process takes time and skill to get right.

Always look for certificates of analysis (COAs) and results from third party lab analysis.

Final Thoughts on THCV Effects

We are just beginning to learn about THCV’s effects, what they are, and how we can take advantage of them. But for now, who isn’t curious about diet weed?!

Disclaimer: Remember, cannabis products are only for people 21 years of age and older. Nothing in this post is medical advice or can take the place of a visit with a healthcare professional.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

THC-O vs THC-P

What are the main differences between THC-O and THCP? In this post, we explain what each compound is, what its basic effects are, and compare them to other hemp plant cannabinoids. We also cover safety, legality, and where to buy these new cannabinoids.

What are THC-O and THC-P?

THC acetate ester (THC-O acetate or just THC-O) and tetrahydrocannabiphorol (THCP) are both analogs of delta-9 THC molecule found in the Cannabis sativa plant. Each one is perhaps best for seasoned cannabis users since they are stronger than the classic delta-9 tetrahydrocannabinol (THC) you’re used to.

THC-O and THCP are both derived from the class of “tetrahydrocannabinols.” This group of compounds includes different versions of THC, such as delta-7, delta-8, delta-9, delta-10 THC, HHC, and THCV. However, THC-O and THCP are not the same.

THC-O is a semi-synthetic cannabinoid and a prodrug which means it becomes active only after metabolization. It doesn’t naturally occur in cannabis plants. Manufacturers typically synthesize THC-O concentrates in laboratories from tetrahydrocannabinolic acid (THCA). THC-O produces a deep sense of euphoria and in large doses can induce hallucinogenic effects.

In contrast, THCP is present in certain cannabis strains as a cannabinoid synthesized in nature. Although THC-P occurs in cannabis strains at high levels, it is actually active already before it enters the body. While it doesn’t cause hallucinations, the chemical structure of THCP produces stronger psychedelic effects than THC-O thanks to its longer alkyl side-chain.

How do THC-O and THC-P compare head to head? THCP is stronger than THC-O—about 200% more potent. Of course, THC-O is still three times stronger than regular THC, and in high doses it can induce hallucinations. For this reason, some use THC-O as a spiritual experience.

Remember, none of these cannabinoids is for beginners. Expect that the side effects of THC-O and THCP will be a lot like THC—and then some. If you are new to derivatives and analogs we recommend trying delta-8 THC first.

The colorless, highly flammable chemical compound acetic anhydride is used to synthesize THC-O. It is typically used in making dyes, explosives, fibers, pharmaceuticals, and plastics.

How Were THC-O and THCP Discovered?

The US Army discovered THC-O during the Edgewood Arsenal Experiment in the 1940s on dogs. THCP was discovered much later, by the Italian military, in 2019, who also discovered CBDP, an analog of cannabidiol (better known as CBD).

How Do THC-O and THCP Work?

THC-O and THCP interact with CB1 receptors in the brain and central nervous system. These receptors are part of the endocannabinoid system (ECS), a vast neurochemical network.

The ECS regulates core bodily functions, including appetite, body temperature, fear perception, fertility, immune responses, memory, mood, pain, sleep, etc. The CB1 receptor mediates the euphoric high, also provides health benefits, including anti-inflammation, neuroprotection, pain relief, physical and mental relaxation, and sleep improvements.

Does THC-O Get You Higher than Naturally Occurring Cannabinoids?

No, it’s just the opposite. Although THC-O is 300% stronger than delta-9 THC, THCP is 2x stronger than THC-O, about ten times stronger than delta-9 THC and 15 times stronger than delta-8 THC.

An alkyl side chain, also called the main or primary chain or backbone, is a string of carbon atoms that influence how the body’s cannabinoid receptors and cannabinoids interact. The length of the alkyl side chain of THCP is at the root of its extreme potency. For perspective, THC-O has an alkyl side chain with five-links, while THCP has an alkyl side chain with seven-links. Thus, THCP has the most binding ability with these receptors, and is the strongest THC analog.

Anecdotal evidence suggests that THCP creates similar effects as delta-9, plus additional mental and physical effects. However, even in high doses, THCP doesn’t cause hallucinations, unlike THC-O.

The onset and type of effects depend on the product type:

  • Vape carts. Vape liquids are infused with THC-O and sometimes terpenes to create THCP distillate vapes and other inhalables. The effects start within minutes and last for up to 4 hours.
  • Tinctures. Oils and tinctures offer high bioavailability and a rapid onset of effects—usually users feel the effects of THCP or THC-O within 30 minutes.
  • Edibles. Edibles like THC-O gummies are ingested orally, which causes the cannabinoids to take longer before they start showing effects—usually between 30–90 minutes, depending on metabolism and whether they were consumed with or without food. Edibles also sometimes produce more powerful effects that last longer than other forms of THC.

THC-O vs. THCP: Are They Legal?

The legal status of any cannabinoids, including THC-O and THCP, can be confusing.

The Controlled Substances Act (CSA) only touches on delta-9 THC, and doesn’t specify these cannabinoids. However, parts of the Federal Analogue Act (FAA) do cover THC analogs, which means that without further action all THC isomers would be scheduled substances.

However, the 2018 Farm Bill made hemp-derived cannabinoids legal, including THC analogs. The bill specifies that all hemp products are legal so long as they are derived from hemp plants that have < 0.3% delta-9 THC.

This made hemp-derived cannabinoids such as THCP, THC-O, HHC, and delta-8 THC legal across the US federally. Specific states have banned products containing these compounds or imposed 0.3% limits on all THC variants.

It is worth noting that the Drug Enforcement Administration (DEA) has not clearly defined “synthetic” in its regulations, but may be working to create a rule limiting the use of cannabinoids such as THC-O and THC-P. This would be based on the fact that THC-O is produced in a laboratory; according to a 2017 DEA Resource Guide, if they are made in a laboratory, “synthetic cannabinoids are not organic.” If the DEA clarifies its definition of synthetic, it may also move to define hemp-derived THC-O as a controlled substance.

What About Marijuana-Derived THC-O and THCP?

Marijuana-derived cannabinoids, including THC-O and THCP, are all illegal federally under the Controlled Substances Act. The law prohibits all products derived from cannabis plants with delta-9 THC levels that exceed 0.3% by dry weight. This makes it illegal to grow, manufacture, package, distribute, sell, possess, buy, import, and transport cannabis products under federal law.

However, marijuana laws also differ from state to state. Check your local and state laws to ensure hemp-derived cannabinoids like delta-8 THC, THC-P, and THC-O are legal where you live.

Are THCP and THC-O Safe?

Both THC-O and THCP can be attractive low-dose options if you want something other than delta-9 THC. But since manufacturers must extract usable amounts of THC-O and THCP from cannabis, you need to ensure your THCP and THC-O products are free from contaminants. Always check the certificate of analysis (CoA), and only buy from trusted vendors.

How Do All of the Cannabinoids Compare?

Wondering how THC-O and THCP compare to other popular and legal hemp-derived cannabinoids?

THC-O and THCP create greater psychoactive effects than the cannabinoid hexahydrocannabinol (HHC) which occurs in nature and has a similar strength to delta-9 THC. THCP is about 10 times stronger than HHC, while THC-O is about 5 times stronger. For a more familiar frame of reference, HHC is about 80% as potent as delta-9 THC. HHC is known for its soothing, relaxing effects, particularly when combined with CBD.

Both THCP and THC-O are stronger than delta-8. THCP is 15x stronger than delta-8, while THC-O is approximately 5x more powerful.

At any dose, delta-8 offers a relaxing high and mild psychoactive effects. For first time users, delta-8 THC is often the smartest analog, especially for anyone who might be sensitive to the effects of delta-9 THC.

While you can mix THC-O and THCP with alcohol, we don’t recommend doing it. Alcohol, especially binging on it, can worsen the side effects of any kind of THC.

CBD is found in much larger concentrations in cannabis than either THCP or THC-O, and neither of them share many characteristics with CBD. CBD doesn’t interact with CB1 receptors and so cannot produce intoxicating effects.

Similar to CBD, other cannabinoids that occur in nature but don’t interact with CB1 receptors such as CBG are not intoxicating but may be relaxing and have little in common with either THC-O or THC-P. THCP and THC-O both induce a euphoric high and may cause users to fail a drug test.

Where to Buy THC-O and THCP Products

Because hemp-derived cannabinoids are federally legal, you might be tempted to visit a nearby head shop or vape store and see if they stock THC-O and THCP products. Certainly a dispensary is a better choice, because at least you know more of what you’re getting. But it’s expensive and limits your choices for sure.

You will find the most high-quality THC-O and THCP products online. That’s the easiest way to maximize your selection and verify quality. Like any natural product or supplement, hemp products are not regulated by the US Food and Drug Administration (FDA), so the ability to shop with reputable vendors that offer testing results is key. Reading the COA shows you the levels of cannabinoids and ensures your products are free of trace amounts of solvents and other contaminants.

Finally, when you shop online to buy THC-O and THCP you can compare different flavors, formulas, prices, and potencies right from home, anytime. It feels pretty amazing to get your gummies or vape cartridges right to your door!

Final Thoughts on THC-O vs THCP

THC-O and THCP are still really new, and there’s a lot to learn about them both. When you shop online for THC-O and THCP products from trusted vendors who post third party lab testing results, you know just what you’re getting! You also have a confident, convenient experience.

Learn more about THC-O and THC-P here.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

What is THC-O?

What is THC-O? In this post, we explain what this compound is, what its basic effects are, and compare it to other hemp plant cannabinoids. We also cover safety, legality, and where to buy this new cannabinoid.

Explainer: What is THC-O?

THC acetate ester (THC-O acetate or just THC-O) is an analog of the delta-9 THC molecule. It is sometimes preferred by experienced cannabis users since it is stronger than the classic delta-9 tetrahydrocannabinol (THC) you’re used to.

THC-O is derived from the class of “tetrahydrocannabinols.” This group of compounds includes different versions of THC, such as delta-7, delta-8, delta-9, delta-10, HHC, THC-P, and THCV. However, THC-O is unique.

THC-O is a semi-synthetic cannabinoid and a prodrug which means it becomes active only after metabolization. It doesn’t naturally occur in cannabis plants. Manufacturers typically synthesize THC-O concentrates in laboratories from tetrahydrocannabinolic acid (THCA). THC-O produces a deep sense of euphoria and in large doses can induce hallucinogenic, psychedelic effects.

How does THC-O compare to regular THC? THC-O is about three times stronger than regular THC, and in high doses it can induce hallucinations. For this reason, some use THC-O as a spiritual experience.

Remember, none of these cannabinoids is for beginners. Expect that the side effects of THC-O and THCP will be a lot like THC—and then some. If you are new to derivatives and analogs, delta-8 THC is another good alternative.

How Was THC-O Discovered?

The US Army discovered THC-O during the Edgewood Arsenal Experiment in the 1940s on dogs. The colorless, highly flammable chemical compound acetic anhydride is used to synthesize THC-O. It is typically used in making dyes, explosives, fibers, pharmaceuticals, and plastics.

(This is not to be confused with THCP, which was discovered much later in 2019 by the Italian military, who also discovered CBDP, an analog of cannabidiol [CBD]).

How Does THC-O Work?

THC-O interacts with CB1 receptors in the brain and central nervous system. These receptors are part of the endocannabinoid system (ECS), a vast neurochemical network.

The ECS regulates core bodily functions, including appetite, body temperature, fear perception, fertility, immune responses, memory, mood, pain, sleep, etc. The CB1 receptor mediates the euphoric high, also provides health benefits, including anti-inflammation, neuroprotection, pain relief, physical and mental relaxation, and sleep improvements.

Does THC-O Get You Higher than Other Forms of THC?

Yes, THC-O is much stronger than delta-9 THC and delta-8 THC, though not THC-P.

An alkyl side chain, also called the main or primary chain or backbone, is a string of carbon atoms that influence how the body’s cannabinoid receptors and cannabinoids interact. The length of the alkyl side chain of THCP is at the root of its extreme potency. For perspective, THC-O has an alkyl side chain with five-links, while THCP has an alkyl side chain with seven-links. Thus, THCP binds the most readily with these receptors, and is the most potent THC analog.

Anecdotal evidence suggests that THCP creates similar effects as delta-9, plus additional mental and physical effects. However, even in high doses, THCP doesn’t cause hallucinations, unlike THC-O.

The onset and type of effects depend on the product type:

  • Vape carts. Vape liquids are infused with THC-O and sometimes terpenes to create distillate vapes and other inhalables. The effects start within minutes and last for up to 4 hours.
  • Tinctures. Oils and tinctures offer high bioavailability and a rapid onset of effects—usually users feel the effects of THC-O within 30 minutes.
  • Edibles. Edibles like THC-O gummies are ingested orally, which causes the cannabinoids to take longer before they start showing effects—usually between 30–90 minutes, depending on metabolism and whether they were consumed with or without food. Edibles also sometimes produce more powerful effects that last longer than other forms of THC.

THC-O Products: Are They Legal?

The legal status of any cannabinoids, including THC-O, can be confusing.

The Controlled Substances Act (CSA) only touches on delta-9 THC, and doesn’t specify these cannabinoids. However, parts of the Federal Analogue Act (FAA) do cover THC analogs, which means that without further action all THC isomers would be scheduled substances.

However, the 2018 Farm Bill made hemp-derived cannabinoids legal, including THC analogs. The bill specifies that all hemp products are legal so long as they are derived from hemp plants that have < 0.3% delta-9 THC.

This made hemp-derived cannabinoids such as THCP, THC-O, HHC, and delta-8 THC legal across the US federally. Specific states have banned products containing these compounds or imposed 0.3% limits on all THC variants.

It is worth noting that the Drug Enforcement Administration (DEA) has not clearly defined “synthetic” in its regulations, but may be working to create a rule limiting the use of cannabinoids such as THC-O. This would be based on the fact that THC-O is produced in a laboratory; according to a 2017 DEA Resource Guide, if they are made in a laboratory, “synthetic cannabinoids are not organic.” If the DEA clarifies its definition of synthetic, it may also move to define hemp-derived THC-O as a controlled substance.

What About Marijuana-Derived THC-O?

Marijuana-derived cannabinoids, including THC-O, are all illegal federally under the Controlled Substances Act. The law prohibits all products derived from cannabis plants with delta-9 THC levels that exceed 0.3% by dry weight. This makes it illegal to grow, manufacture, package, distribute, sell, possess, buy, import, and transport cannabis products under federal law.

However, marijuana laws also differ from state to state. Check your local and state laws to ensure hemp-derived cannabinoids like delta-8 THC and THC-O are legal where you live.

Is THC-O Safe?

THC-O can be attractive low-dose options if you want something other than delta-9 THC. But since manufacturers must extract usable amounts of THC-O from cannabis, you need to ensure your THC-O products are free from contaminants. Always check the certificate of analysis (CoA), and only buy from trusted vendors

How Do All of the Cannabinoids Compare?

Wondering how THC-O compares to other popular and legal hemp-derived cannabinoids?

THC-O creates greater psychoactive effects than the cannabinoid hexahydrocannabinol (HHC) which occurs in nature and has a similar strength to delta-9 THC. THC-O is about 5 times stronger than HHC. For a more familiar frame of reference, HHC is about 80% as potent as delta-9 THC. HHC is known for its soothing, relaxing effects, particularly when combined with CBD.

THC-O is approximately 5x more powerful than delta-8. At any dose, delta-8 offers a relaxing high and mild psychoactive effects. For first time users, delta-8 THC is often the smartest analog, especially for anyone who might be sensitive to the effects of delta-9 THC.

While you can mix THC-O with alcohol, we don’t recommend doing it. Alcohol, especially binging on it, can worsen the side effects of any kind of THC.

CBD is found in much larger concentrations in cannabis than THC-O, they two share few characteristics. CBD doesn’t interact with CB1 receptors and so cannot produce intoxicating effects. THC-O induces a euphoric high and may cause users to fail a drug test.

Where to Buy THC-O Products

Because hemp-derived cannabinoids are federally legal, you might be tempted to visit a nearby head shop or vape store and see if they stock THC-O \ products. Certainly a dispensary is a better choice, because at least you know more of what you’re getting. But it’s expensive and limits your choices for sure.

You will find the most high-quality THC-O products online. That’s the easiest way to maximize your selection and verify quality. Like any natural product or supplement, hemp products are not regulated by the US Food and Drug Administration (FDA), so the ability to shop with reputable vendors that offer testing results is key. Reading the COA shows you the levels of cannabinoids and ensures your products are free of trace amounts of solvents and other contaminants.

Finally, when you shop online to buy THC-O you can compare different flavors, formulas, prices, and potencies right from home, anytime. It feels pretty amazing to get your gummies or vape cartridges right to your door!

Final Thoughts on THC-O

THC-O is still really new, and especially if you’re curious about psychedelics you’re probably dying to try it. When you shop online for THC-O products from trusted vendors who post third party lab testing results, you know just what you’re getting! You also have a confident, convenient experience.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

THCC

Have you heard about tetrahydrocannabiorcol (THCC) yet? In spite of its name, THCC is not that much like classic THC. It’s more like CBD, non-psychoactive, and targets similar receptors as CBC, CBD, and CBG.

Here’s the scoop on this trending phytocannabinoid in the cannabis news.

What is THCC?

THCC is a cannabinoid that occurs naturally in both cannabis plants and hemp plants.

It has a similar chemical structure to THC and is created as the plant matures through similar chemical processes.

At the molecular level, THCC and THC are nearly identical, with the exception of three carbon atoms that dramatically change their effect profiles. THC exerts its psychoactive effects by activating the CB1 receptors, which THCC cannot do. THCC appears to work more like CBD, upregulating the naturally occurring endocannabinoids in the body and interacting with receptors called the TRP channels.

Is THCC Synthetic?

No, THCC is a phytocannabinoid, meaning it is found naturally in the hemp or cannabis plant, independent from human intervention. Specifically, unlike THC, which is found in the resin produced on the female flowers, THCC is found in cannabis and hemp pollen.

Where Does THCC Come From?

Many cannabinoids start as cannabigerolic acid (CBGA). CBGA goes through several enzymatic reactions as the plant matures and this changes it to other acidic molecules that are precursors to biologically active compounds such as THC and THCC. Tetrahydrocannabiorcolic acid (THCCA) is the precursor molecule that gets converted to THCC during a process called decarboxylation over the course of a cannabis or hemp plant’s life cycle.

Typically, manufacturers extract THCC from hemp or cannabis pollen and use the extract to  make concentrate. It’s a similar process to making other cannabinoid concentrates.

Scientific Research Into THCC

The bulk of research into THCC is focused on cannabis, cannabinoids, and the endocannabinoid system generally. Here are some of the most important articles to consider:

Medicinal Chemistry of Cannabinoids: This review offers a basic overview of the endocannabinoid system, the cannabinoid receptors in it, and cannabinergic agents being explored clinically in drug research.

Cannabinoid Modulation of Drug Reward and the Implications of Marijuana Legalization: This article found in Brain Research focuses on the brain endocannabinoid (eCB) system, mesolimbic dopamine function, and conditioned reinforcing properties of cues predicting reward or punishment.

Cannabis’s Chemical Synergies: In this article from Nature Communications, there is a thorough discussion of the entourage effect (cannabinoids, terpenes, and how they work together).

The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation: Finally, this article focuses on the chemical structure of cannabinoids and how they function.

Is THCC Legal?

Delta-9 THC—the classic THC we know and love from cannabis—is the only internationally regulated cannabinoid. These marijuana laws sometimes explicitly exclude all forms of THC, including delta 8, delta 10, and THCC, but not always

In the United States, as long as it’s derived from hemp, THCC is federally legal. This by definition assumes it contains no more than 0.3% delta 9 THC because hemp in the US is defined to include less than 0.3% THC by dry weight.

Each state controls THC analogs, including THCC, so it pays to check first.

THCC vs THC

Based on the names, it would be easy to confuse THC and THCC or think the molecules were basically identical—but they’re not.

THC and molecules similar to it have a key molecular feature that controls their biological activity called an alkyl side chain. The strength of the psychoactive effects is controlled by the length of this side chain; molecules with more psychoactive effects have longer chains, while THCC only has one. For example, mildly psychoactive THCV has 3 carbons, delta-8, 9, and 10 THC have 5-carbon side chains, and the highly psychoactive THCP has 7 carbons.

How Does THCC Work?

THCC produces effects most like CBD. They are relaxing, pleasant, and soothing similar to those you might feel using delta-8 THC but with no trace of psychoactivity. This is because THCC does not involve the CB1 or CB2 receptors in the endocannabinoid system and instead activates the TRP receptors such as TRPA1 on gated ion channels on the cell wall. These play a role in temperature regulation, pain perception, and nerve cell regeneration.

Type 1 cannabinoid receptors (CB1) are related to the brain and central nervous system (CNS) and produce the psychotropic and euphoric effects of THC. Type 2 cannabinoid receptors (CB2) are focused in the organs, peripheral nervous system, and immune cells.

However, in contrast to the more psychoactive cannabinoids such as THC and more like CBD, THCC has no affinity for CB1 or CB2 receptors, meaning it amplifies the effects of naturally occurring endocannabinoids like 2-AG and anandamide and doesn’t produce a high.

Does THCC Get You High?

No. In fact, unlike with other THC products, you’re not going to feel high no matter how much of this cannabinoid you take.

Unlike THC, THCC doesn’t have any psychoactive properties because it has a shorter alkyl chain and does not interact with the body’s CB1 receptors.

Final Thoughts on THCC

THCC is just one of many exciting new cannabis and hemp related options on the market today. It’s a naturally occurring compound, but unlike THC, THCC does slightly different things in the body and mellows you out in a non-psychoactive way. More like CBD than THC, many people like the way this new option makes them feel.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

THCP Effects

Have you been curious about what kind of effects one of the most powerful cannabinoids around produces? Read on to learn all about THCP:

  • What is THCP?
  • What are THCP’s effects?
  • Where to find THCP
  • THCP vs THC and other cannabinoids

What is THCP?

Found in some strains of the Cannabis sativa plant at very low concentrations, 9-tetrahydrocannabiphorol (THCP) is a potent, recently discovered cannabinoid. Abbreviations for this analog of THC include THCP, THC-P, THCp, and delta-p.

A team of researchers in Italy accidentally discovered it using mass spectrometry in 2019, although this particular cannabis strain is not unique. Manufacturers soon learned that, like all other cannabinoids, THCP starts out as CBGA. This means it can be extracted from legal hemp-derived CBD in a lab via chromatography. However, THCP is more like tetrahydrocannabinol (THC) than CBD in terms of its effects.

Since delta-8 THC and a whole variety of hemp-derived cannabinoids have changed the face of the cannabis industry, they’ve been joining delta-9 THC in traditional cannabis strains and products on the shelves. These other cannabinoids are really growing in popularity, and offering consumers new experiences.

For example, an isomer like delta 8 THC or THCV might be thought of as “diet” weed of the cannabis plant; cannabinoids like like HHC or delta 10 THC are milder, stress relieving medical cannabis alternatives; and THC-O is sometimes thought of as the psychedelic cannabinoid.

Researchers, patients, and recreational users alike are just starting to learn about the potential of THCP. And people who love cannabis and cannabinoids are already parsing out all of the differences by trying them.

Does THCP get you high?

Obviously, delta 9 THC is the king of cannabinoids that naturally occurs in most cannabis strains in the greatest abundance. However, there are over one-hundred organic phytocannabinoids including THCP, each with a slightly different chemical structure and incident effects.

Specifically, compared to delta 9 THC, THCP has a longer alkyl side chain with seven carbon atoms, and this different molecular structure allows THCP to bind more readily with the human CB1 and CB2 endocannabinoid receptors. THCP is usually extracted from CBD and legal hemp plants in a laboratory.

The same Italian researchers who made the accidental discovery also experimentally established that THCP binds 33 times more handily with human CB1 receptors in the endocannabinoid system (ECS) than delta 9 THC, likely due to its extended seven-atom side chain. The CB1 cannabinoid receptor, central to producing psychoactive effects, is found mostly in the brain and the central nervous system (CNS). THCP also binds more readily with the CB2 receptor, found elsewhere in the body and responsible for pain management.

What are the effects of THCP?

Because THCP binds so well with the cannabinoid receptors, it produces effects that feel qualitatively similar but stronger than classic delta 9 THC. For example, the research into THCP  showed that mice taking higher doses of this new cannabinoid experienced pain relief and displayed a trance-like state.

In fact, it is entirely possible that tiny amounts of THCP in some of the cannabis strains we already know well may partly contribute to their healing powers. This powerful binding affinity could also be responsible for amplifying some of the less pleasant side effects of the cannabis plant such as anxiety, dry mouth and eyes, and paranoia.

[Learn more about THCP from the 2019 study here—but realize there has been no research into side effects or benefits in humans, so what we know can only be extrapolated from what is known about other cannabinoids and forms of THC.]

But this may not be as confounding as we imagine, because other hemp derived cannabinoids are already in most THCP products—not to mention most cannabinoid products currently available. There is no real way to know whether what is in a product is hemp-derived cannabinoids, naturally occurring cannabinoids, or both. In reality, the difference is not always clear.

For example, the researchers who discovered THCP in 2019, also isolated cannabidiphorol (CBDP) in their sample. An analog of cannabidiol (CBD), CBDP has a similar chemical structure to that of THCP, with a seven-atom side chain.

Will THCP show up in a drug test?

Although it is not 100% certain that THCP will appear on a drug test, you should avoid THCP if you are subject to testing. This is because along with all forms of THC (except pure CBD) and all other hemp derived cannabinoids, it may trigger a positive result.

Is THCP legal and where is it sold?

Congress legalized hemp, its derivatives, and any extracts and compounds made from hemp with the 2018 Farm Bill. A federal court has confirmed the legality of delta 8 THC all hemp products that have less than 0.3% delta 9 THC which extends to other hemp-derived products.

How can you buy THCP products?

There are vape pens with THCP, and THCP edibles like gummies and tinctures. Edibles are probably the most popular choice, because they’re delicious and convenient. Plus, although vapes are out there, THCP vape carts can be seriously potent!

Some states ban or restrict hemp-derived cannabinoids themselves, or regulate them for sale by licensed cannabis dispensaries only. In other places you can find all kinds of products with cannabinoids everywhere from gas stations to convenience stores.

But honestly, the better selections of hemp-derived cannabinoid products are almost always with online retailers. We sell THCP products and all of the other cannabinoids out there—and we have the highest quality.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

What is THCP?

Found at very low concentrations in some strains of the Cannabis sativa plant, THCP is a recently discovered cannabinoid. It was found accidentally in 2019 by a team of Italian researchers as they analyzed a specific cannabis strain.

Although like all cannabinoids THCP begins as CBGA, it can be made in a lab from legal hemp-derived CBD. This does not mean THCP is not intoxicating; it is more akin to tetrahydrocannabinol (THC) in its effects than CBD. Abbreviations for this analog of THC include THC-P, THCP, THCp, and delta-p.

Since delta-8 THC has taken the cannabis industry by storm, a variety of hemp-derived cannabinoids have joined the delta-9 THC that you find in traditional cannabis strains on the shelves. These other cannabinoids are all growing in popularity.

For example, THCV is often thought of as “diet” weed, as is delta 8 THC; delta 10 THC is a mild, de-stresser like HHC; and THC-O is known as the psychedelic cannabinoid. These are all popular fruits of the cannabis plant, and THCP is ready to join them.

THCP (not to be confused with THCC) may offer recreational users a potent new high, not to mention medical marijuana patients new therapeutic benefits. Researchers are just starting to learn about the potential of THCP.

What is THCP?

THCP is an organic phytocannabinoid much like delta 9 THC, the cannabinoid that occurs naturally in the greatest abundance in most cannabis strains. Although it is a natural cannabinoid, THCP is usually extracted from CBD and legal hemp or cannabis plants in a laboratory.

THCP has a different molecular structure compared to delta 9 THC. Specifically, THCP binds more readily with human CB1 and CB2 cannabinoid receptors, because it has a longer alkyl side chain with seven carbon atoms.

Does THCP get you high?

The Italian researchers who first identified THCP found experimentally in human tissue that, perhaps due to its extended seven-atom side chain, THCP binds 33 times more effectively with human CB1 receptors in the endocannabinoid system (ECS) than delta 9 THC. The CB1 cannabinoid receptor is central to producing psychoactive effects, although THCP also binds more handily with the CB2 receptor.

What are the effects of THCP?

THCP binds well with cannabinoid receptors, so it produces effects that are similar but perhaps stronger than delta 9 THC in some ways. The research into this new cannabinoid showed that mice displayed a trance-like state at higher doses. THCP also offered pain relief at higher doses.

In fact, minuscule amounts of THCP in well-known cannabis strains may be partly responsible for the known healing powers of the cannabis plant. This powerful binding effect could also mean that less pleasant THC side effects—such as anxiety, dry mouth and eyes, and paranoia—might also be amplified.

[You can read about THCP in the 2019 study here, although there is still no human research into side effects, so this can only be extrapolated from what is known about other forms of THC.]

Most THCP products currently available also contain other hemp-derived cannabinoids. For example, the team who discovered THCP in 2019, also found cannabidiphorol (CBDP) in the same sample of cannabis. CBDP is an analog of cannabidiol (CBD) with a seven-atom side chain similar to the chemical structure found on THCP.

You can never be sure whether you are buying naturally occurring cannabinoids or hemp-derived cannabinoids. In truth, it is not clear what the difference is.

Will THCP show up in a drug test?

It is not clear whether THCP will appear on a drug test, but you should avoid THCP if you are subject to testing along with all other hemp derived cannabinoids and all forms of THC (except pure CBD).

Is THCP legal and where is it sold?

With the 2018 Farm Bill Congress legalized hemp and its derivatives and compounds that have less than 0.3% delta 9 THC. A federal court has confirmed that delta 8 THC is also legal, and this appears to extend to other hemp-derived products.

Some states have restricted hemp-derived cannabinoids on their own, or kept them to licensed cannabis dispensaries. Other states may follow Oregon’s example and ban all THCP and all cannabinoids they claim are “artificially derived.

How can you buy THCP products?

Buying THCP can be confusing since it’s new to the hemp-derived cannabinoid marketplace. Most products called THCP really contain THCP mixed with other, more common hemp-derived cannabinoids like delta 8 THC that are cheaper to come by.

There are disposable vapes and standard vape pens with THCP, and THCP edibles like gummies and tinctures. Edibles are probably the most common products, and although vapes are out there, be advised that THCP vape cartridges can also be potent!

The online retailers that have the better selections of hemp-derived cannabinoid products usually sell THCP products. We also have the highest quality!

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

Is Delta 8 Indica or Sativa?

  • Delta-8 strains tend to be classified as sativa, indica, or hybrid.
  • The best delta-8 THC strain for any one person depends on desired effects, preference, and whatever you might be treating, if anything.
  • Trial and error is one of the easiest ways to choose the delta-8 THC strains you like most, but it’s also a safe bet to start with popular strains like Pineapple Express or Gorilla Glue.
  • In states where delta-8 is legal, buy delta-8 THC in stores, but online shopping gives a much better variety of delta-8 strains.

How Does Delta 8 Affect the Endocannabinoid System?

All mammals have an endocannabinoid system, a complex biological cell-signaling system with receptors that bind with endocannabinoids or cannabinoids to produce effects in the nervous system. Delta 8 tetrahydrocannabinol (THC), one of those cannabinoids, occurs in nature, yet even full-spectrum cannabis strains do not produce over 1% delta 8 by weight. 

Full spectrum products contain a complete profile of terpenes and cannabinoids. Together these compounds interact to produce the entourage effect. When they are hemp-derived they contain less than 0.3% delta-9 THC by dry weight—but it is still present, like other cannabinoids in small concentrations such as delta 7, delta 10 THC, or HHC.

What is Delta 8 Flower?

Delta 8 flower is usually made by adding delta 8 THC distillate to cannabis flower. (This is the same product found in delta 8 THC vape cartridges.) This is how you achieve popular strains and high delta 8 content in delta 8 pre-rolls and similar products. You can even find delta 8 THC moon rocks—D8 distillate coated in delta 8 THC kief—in some places.

How is Delta 8 Used?

Because delta 8 THC isn’t abundant in nature, it’s usually extracted from legal hemp plants using an isomerization process. When Delta 8 is extracted from the hemp plant it’s a sticky liquid that then goes through a purification process to remove unwanted contaminants while preserving the cannabinoids.

The result is delta 8 THC distillate: almost totally pure delta 8 THC for various products, such as delta 8 gummies, delta 8 carts, softgels, tinctures, etc. Delta 8 distillate can also be vaped by consumers at home or even used in baking and cooking, and you can make it just like you use distillate to make CBD gummies and similar edibles. There are many ways to use delta 8 concentrate once you get it home from the dispensary or get that package in the mail.

Is Delta 8 THC Flower Legal?

Delta 8, because hemp-derived, is legal at the federal level based on the 2018 Farm Bill. This law defined hemp and hemp products with less than 0.3% of their dry weight as delta-9 THC as legal. However, you should always check the local legality of delta 8 before you buy anything. Also, be aware that delta-8 products are not regulated by the US Food and Drug Administration (FDA). This just makes label reading extra important—as it is with all cannabis products!

How Does Delta 8 THC Compare With Delta 9 THC?

Delta 8 THC is an analog of the world’s most famous cannabinoid, delta 9 THC. Although they are similar in many ways, they are structurally and chemically different and therefore produce slightly different effects.

The effects of Delta 8 are much less psychoactive, for example, which is driving its popularity in the CBD product space. Delta 8 THC also occurs much more rarely in nature than Delta 9 THC, and regardless of the cannabis strain, its concentrations reach only 1 percent.

Indica, Sativa, or Hybrid: How to Choose the Right Strains

People often think, what’s better, sativa vs indica, but in reality strains differ most based on things like terpene profile. Still, starting with whether a strain is a sativa, indica, or hybrid gives you an understanding of the basics of what other people get from it. In other words, users of cannabis and its cannabinoids have a general sense of indica effects and sativa effects, and rate and characterize strains based on those ideas.

Indica Delta 8 THC Strains

Cannabis indica strains are classically associated with relaxing effects and a body high. This species of cannabis plant is also usually higher in cannabidiol (CBD), which can offset the negative side effects of THC and help with pain relief. For the Netflix and chill group, these indica strains are perfect (but if you’re worried about being couch-locked, steer clear).

Sativa Delta 8 THC Strains

Cannabis sativa strains of hemp flower are more uplifting and energizing. Most sativa strains have higher concentrations of THC and may enhance productivity and creativity, and make social settings easier.

Hybrid Delta 8 THC Strains

For many people, hybrid strains are the best of all worlds, crossing sativa Delta-8 and indica strains to get the specific traits and more balanced effects users seem to like most. Some people have a more healthcare focused take on the benefits, others have a more recreational set of goals—and hybrids offer plenty of chances for you to achieve all of them.

These interesting strains often combine one each sativa plant and indica plant parent, although a true 50/50 indica to sativa is rare. Almost all hybrids are either indica-dominant or sativa-dominant. Choose an indica-leaning hybrid if you’re more into mellow, relaxing effects but you don’t want to feel sedated to couch-locked. Choose a sativa-leaning hybrid if you want to feel awake and alert—but not too anxious.

Third-Party Lab Testing

Look for lab test results as you shop for delta 8 THC of any strain. These results should be clearly displayed; make sure there’s nothing you don’t want in that product, from additives to contaminants.

Does Delta 8 Show Up on a Drug Test?

Yes, any kind of THC from THC-O to delta 8 will be positive on a drug test in most cases.

Final Thoughts on Delta-8 Strains

So, is delta-8 THC indica or sativa? In a sense, it’s whatever the originating plant was, or whatever it’s added to! Or, more precisely, it may produce either indica effects or sativa effects depending on the kind. Find out more about our delta-8 THC strains here.

Written by Diet Smoke Staff Writers

The staff writers for Diet Smoke have been researching and writing about premium hemp-derived THC and CBD products for more than 3 years. The team has a keen understanding of the topic, remain current on all FDA and industry news, and use their expertise to generate engaging and informative content to help educate consumers on Diet Smoke’s products. Each article is fact-checked and includes sources to scientific data to ensure readers receive the most up-to-date and accurate information possible.

Find out more about Diet Smoke, our history and our commitment to creating the highest quality products.

Reviewed By Colby Wohlleb

Colby Wohlleb, editor of Diet Smoke, reviews and approves all content before releasing it for posting on the Diet Smoke website. As a tireless advocate for the benefits of premium hemp-derived THC and CBD products, Colby ensures that all content is accurate, engaging, and informative. He also works directly with a trusted source to ensure the purity of the products we sell and performs rigorous lab testing to ensure that Diet Smoke’s products are of the highest quality and safety standards.

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